Fluoro Buterophenones: Haloperidol, Droperidol, Risperidone : Pharmaguideline

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Fluoro Buterophenones: Haloperidol, Droperidol, Risperidone

The discovery of fluoro butyrophenones has created a new class of psychotropic drugs.
Fluoro butyrophenones: a new class of psychotropic drugs
  • The discovery of fluoro butyrophenones has created a new class of psychotropic drugs.
  • These molecules are structurally similar to amphetamines, but they have a fluorine atom in place of the methyl group.
  • This change results in a significantly less likely molecule to be metabolized by the body and has a much longer half-life.
  • As a result, fluoro butyrophenones are much more potent than amphetamines and have the potential to be abused.
  • However, their ability to increase alertness and energy levels make them attractive to people who want to get high.
  • It is essential to be aware of these drugs and take steps to protect yourself and your loved ones from their potential dangers.
  • If you or someone you know is using fluoro butyrophenones, it is essential to get help as soon as possible.

Fluoro butyrophenones: Haloperidol
  • Haloperidol is a dopamine antagonist typically used to treat schizophrenia and other mental disorders.
  • Haloperidol helps regulate dopamine levels in the brain, which can reduce the symptoms of mental disorders.
  • While haloperidol effectively treats mental disorders, it can also cause several side effects, including drowsiness, dry mouth, and weight gain.
  • Oxidative N-dealkylation metabolizes it.
  • 4-flurobenzoyl propionic acid and 4-Fluro phenylacetic acid are the primary metabolites that help.
  • Haloperidol is a safe and effective medication when used as prescribed.
  • However, it can be addictive and should not be taken without supervision. If you are struggling with addiction to haloperidol, many resources are available to help you get your life back on track.

Fluoro butyrophenones: Droperidol
  • Droperidol is a medication used to treat psychotic episodes and nausea and vomiting.
  • Droperidol helps regulate dopamine levels in the brain, which can reduce the symptoms of mental disorders.
  • While droperidol effectively treats psychotic episodes and nausea and vomiting, it can also cause side effects, including drowsiness, dry mouth, and weight gain.
  • Droperidol should be taken exactly as directed by your doctor, and any side effects should be reported right away.
  • Droperidol is a safe and effective medication when used as prescribed. However, it can be addictive and should not be taken without supervision.

If you are struggling with addiction to droperidol, many resources are available to help you get your life back on track.

Assay: Dissolve the sample in a mixture of 1 volume of anhydrous acetic acid and 7 volumes of methyl ethyl ketone. Titrate with 0.1 M perchloric acid, using naphthol benzene solution, and endpoint is the color change from orange-yellow to green.

Storage: It should be kept in an airtight container kept away from light.

Dosage forms: Droperidol injection B.P., Droperidol tablets B.P.

Fluoro butyrophenones: Risperidone
  • Many mood disorders and mental disorders are taken care of with the help of the drugs called Risperidone.
  • This drug can assist you in thinking clearly and participating in daily activities.
  • Risperidone belongs to the atypical antipsychotic medical class.
  • Restoring natural substances’ balance of the brain and its assistance is where this drug works.
  • Psychotic episodes, schizophrenia, and bipolar disorder are treated by the drug named Resperidone.
Dopamine is a neurotransmitter responsible for motivation and pleasure experiences, and high dopamine levels can further lead to psychosis and other mental disorders.

Risperidone helps regulate dopamine levels in the brain, which can reduce the symptoms of mental disorders.

While Risperidone effectively treats psychotic episodes, schizophrenia, and bipolar disorder, it can also cause several side effects, including drowsiness, dry mouth, and weight gain.

One should follow their doctor’s instructions for using Risperidone and report any side effects in these cases.

When taken as directed, Risperidone is a safe and effective drug.
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Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of pharmaguideline.com, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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