Preparation and Standardization of 0.1 M Lead Nitrate : Pharmaguideline
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  • Sep 24, 2010

    Preparation and Standardization of 0.1 M Lead Nitrate

    Preparation and standardisation of 0.1 M Lead Nitrate solution using Disodium Edetate and Xylenol Orange mixture as indicator used in chemical analysis of pharmaceutical ingredients.

    Lead Nitrate Solution Preparation

    • Dissolve 33.12 g of lead nitrate in sufficient water to produce 1000 ml.
    • Standardize the solution in the following manner.

    Lead Nitrate Solution Standardization

    • Pipette 50.0 ml of the solution into a flask.
    • Add 50 mg of xylenol orange mixture and sufficient hexamine to produce a violet-pink color.
    • Titrate with 0.1 M disodium edetate to a lemon yellow endpoint.
    • 1 ml of 0.1 M disodium edetate is equivalent to 0.03312 g of Pb(N03)2.
    Also see: Determination of Shelf Life of Solutions in Laboratory

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