Preparation and standardisation of 0.5 M Potassium Hydroxide in 60 % ethanol using Hydrochloric Acid and Phenolphthalein solution as indicator used in pharmaceutical analysis.
Potassium Hydroxide in Ethanol Solution Preparation
- Dissolve 30 g of potassium hydroxide in sufficient ethanol (60 %) to produce 1000 ml.
- Standardize the solution in the following manner.
Potassium Hydroxide in Ethanol Solution Standardization
- Pipette 20.0 ml of standardize 0.5 M hydrochloric acid into a flask.
- Add 0.1 ml of phenolphthalein solution.
- Titrate with the ethanolic potassium hydroxide solution until the permanent pale-pink color is produced.
- 1 ml of 0.5 M hydrochloric acid is equivalent to 0.02806 g of KOH.
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Dr. Ankur Choudhary is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question
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