Preparation and Standardization of 0.05 M Magnesium Sulphate : Pharmaguideline

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Preparation and Standardization of 0.05 M Magnesium Sulphate

Preparation and standardisation of 0.05 M Magnesium Sulphate solution using Disodium Edetate and Mordant Black II mixture as indicator used in pharmaceutical analysis.

Magnesium Sulphate Solution Preparation

  • Dissolve 12.5 g of magnesium sulfate in sufficient water to produce 1000 ml.
  • Standardize the solution in the following manner.

Magnesium Sulphate Solution Standardization

  • Pipette 30.0 ml of solution into a flask.
  • Add 20 ml of water, 10 ml of strong ammonia-ammonium chloride solution and 50 mg of mordant black II Mixture.
  • Titrate with 0.1 M disodium edetate until the color changes from violet to full blue.
  • 1 ml of 0.1 M disodium edetate is equivalent to 0.02465 g of MgS04.7H2O.
Also see: Determination of Shelf Life of Solutions in Laboratory





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of pharmaguideline.com, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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