Preparation and standardisation of 0.02 M Potassium Permanganate using Sodium Thiosulphate and Starch solution as indicator.
Potassium Permanganate Solution Preparation
- Dissolve 3.2 g of potassium permanganate in 1000 ml of water.
- Heat on a water-bath for 1 hour.
- Allow to stand for 2 days and filter through glass wool.
- Standardize the solution in the following manner.
Potassium Permanganate Solution Standardization
- To 25.0 ml of the solution in a glass-stoppered flask add 2 g of potassium iodide, followed by 10 ml of 1 M sulphuric acid.
- Titrate the liberated iodine with 0.1 M sodium thiosulphate, using 3 ml of starch solution, added towards the end of the titration, as an indicator.
- Perform a blank determination and make the necessary correction.
- Store protected from light.
- 1 ml of 0.1 M sodium thiosulphate is equivalent to 0.003161 g of KMnO4.
Also see:
Determination of Shelf Life of Solutions in Laboratory
Dr. Ankur Choudhary is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question
Visitors are also reading:
No comments:
Post a Comment
Please don't spam. Comments having links would not be published.